The Histogenesis of Cartilage and Bone in the Long Bones of the Embryonic Fowl

£350 · Offered by Shapero Rare Books

early tissue culture work by a prominent woman scientist The rare offprint of the first major work by prominent cell biologist Honor B. Fell (1900-1986). We can locate only one institutional copy, at the University of Southern California. Fell's childhood interest in nature was encouraged by her parents, and she received what was at the time an unusually science-focused education. She earned four degrees at St. Andrews and the University of Edinburgh, and then went to Cambridge 'to learn a new technique pioneered by T. S. P. Strangeways in his research hospital. Tissues culture was a relatively new art at this time, and he had developed it to the extent that he could study the behavior of living cells on a warm stage. Fell was impressed, and when Strangeways offered her a job as scientific assistant with a grant from the Medical Research Council, she accepted. Her first major study was on chick embryos, examining their cartilage and bones. This work culminated in her first important paper from the Strangeways in 1925, a study of the histogenesis of bone and cartilage in the long bone of embryonic chicks. From this beginning, she used techniques of organ culture to analyze the actions of various agents upon the cells of bone, cartilage, and associated tissues. The preliminary study was continued, and in 1926 she and Strangeways demonstrated that cartilage would not only grow but would differentiate in culture' (Ogilvie, Biographical Dictionary of Women in Science, p. 440). Whe

• Binding: Hardcover

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